G-protein Coupled Receptors (GPCRs) in Cell Communication

What are the characteristics of G-protein coupled receptors (GPCRs) that make them important for cell communication?

Choose one:

A. 7 ER ; 0 SS

B. 0 ER ; 7 SS

C. 1 ER ; 7 SS

D. 1 ER ; 6 SS

E. 0 ER ; 6 SS

Answer:

G-protein coupled receptors (GPCRs) have 0 ER signal sequences and 6 stop and/or start sequences (SS).

G-protein coupled receptors (GPCRs), also known as seven-transmembrane domain receptors or serpentine receptors, are a large and diverse family of cell surface receptors that play a crucial role in cellular signaling. These receptors are involved in transmitting signals from the extracellular environment to the interior of cells, which can trigger various cellular responses.

GPCRs are important for cell communication as they have 7 transmembrane domains and an N-terminus outside of the cell. GPCRs do not have any ER signal sequences but have 6 stop and/or start sequences (SS), as indicated by the answer being 0 ER ; 6 SS (option E).

These receptors are critical in a wide range of physiological processes, including sensory perception, immune response, neurotransmission, and hormone regulation. Their role in cell signaling makes them essential for proper cellular function and response to external stimuli.