How does isoniazid work in the initial phase of tuberculosis (TB) treatment?

Question:

What action describes how isoniazid works in the initial phase of treatment for tuberculosis (TB)?

Hinders TB enzyme needed for making its DNA and proteins

Interferes with the RNA and protein synthesis of the TB organism

Lowers pH of infected TB cells so they cannot grow and reproduce

Inhibits enzymes of the TB organisms needed for replication and growth

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Not Sure

Answer:

Isoniazid inhibits enzymes of the TB organisms needed for replication and growth.

Isoniazid is a key medication in the treatment of tuberculosis (TB). It works by inhibiting enzymes that are crucial for the replication and growth of TB bacteria. Specifically, isoniazid targets enzymes involved in the synthesis of mycolic acids, which are essential components of the cell wall of TB bacteria.

By disrupting the production of mycolic acids, isoniazid effectively hinders the ability of TB bacteria to replicate and grow. This action is fundamental in the initial phase of TB treatment, as it helps to stop the spread of the infection and reduce the population of TB bacteria in the body.

When used in combination with other TB medications, isoniazid plays a critical role in achieving successful treatment outcomes for TB patients. It is important for patients to adhere to their prescribed treatment regimen to ensure the effectiveness of isoniazid and other anti-TB drugs.